has role diltiazem diltiazemum (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one PMID:19167257 Drug_Central:897 Wikipedia:Diltiazem A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have S configuration. A calcium-channel blocker and vasodilator, it is used as the hydrochloride in the management of angina pectoris and hypertension. diltiazem PMID:25122162 PMID:8369596 Reaxys:3573079 414.51800 PMID:23687551 PMID:16651034 COc1ccc(cc1)[C@@H]1Sc2ccccc2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O PMID:24261918 414.16133 CHEBI:101278 Patent:US4552695 chebi_ontology HMDB:HMDB0014487 0 CHEBI:4602 PMID:11937779 Beilstein:3573079 d-cis-diltiazem CAS:42399-41-7 Patent:DE1805714 (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate LINCS:LSM-2523 InChI=1S/C22H26N2O4S/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3/h5-12,20-21H,13-14H2,1-4H3/t20-,21+/m1/s1 Patent:US3562257 D-cis-diltiazem Patent:DE3415035 C22H26N2O4S KEGG:C06958 (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester KEGG:D07845 Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester DrugBank:DB00343 HSUGRBWQSSZJOP-RTWAWAEBSA-N VSDB:1863 (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate vasodilator agent antihypertensive agent calcium channel blocker diltiazem(1+) ent-diltiazem 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate