has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor roxadustat An <em>N</em>-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH). CHEBI:132774 N-acylglycine renoprotective agent isoquinolines cardiovascular drug antineoplastic agent aromatic ether anti-anaemic agent