has role has functional parent remdesivir CHEBI:145994 A carboxylic ester resulting from the formal condensation of the carboxy group of <em>N</em>-[(<i>S</i>)-{[(2<i>R</i>,3<i>S</i>,4<i>R</i>,5<i>R</i>)-5-(4-aminopyrrolo[2,1-<em>f</em>][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-<small>L</small>-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent <em>in vitro</em> antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults. GS-441524 anticoronaviral agent nitrile phosphoramidate ester aromatic amine antiviral drug C-nucleoside alpha-amino acid ester prodrug pyrrolotriazine