has role berberine CHEBI:16118 geroprotector antioxidant berberine alkaloid hypoglycemic agent EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor antineoplastic agent anticholesteremic drug EC 3.1.1.8 (cholinesterase) inhibitor organic heteropentacyclic compound EC 3.1.1.7 (acetylcholinesterase) inhibitor EC 1.1.1.21 (aldehyde reductase) inhibitor EC 3.1.1.4 (phospholipase A2) inhibitor potassium channel blocker EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor EC 3.4.21.26 (prolyl oligopeptidase) inhibitor EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor EC 1.21.3.3 (reticuline oxidase) inhibitor EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor EC 2.7.11.10 (IkappaB kinase) inhibitor EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor alkaloid antibiotic botanical anti-fungal agent