has role 17alpha-hydroxy-C21-steroid primary alpha-hydroxy ketone tertiary alpha-hydroxy ketone cortisol CHEBI:24633 CAS:50-23-7 362.20932 KEGG:C00735 InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 CHEBI:58221 hidrocortisona Cortisol 17-hydroxycorticosterone cortisol Hydrocortisone Reichstein's substance M LINCS:LSM-5980 CHEBI:3893 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione 0 DrugBank:DB00741 hydrocortisonum LIPID_MAPS_instance:LMST02030001 Drug_Central:1388 11beta,17,21-trihydroxypregn-4-ene-3,20-dione (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione Patent:US2602769 Beilstein:1354819 CHEBI:17650 CHEBI:14023 JYGXADMDTFJGBT-VWUMJDOOSA-N PMID:10438974 [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO Kendall's compound F 4-pregnen-11beta,17alpha,21-triol-3,20-dione KEGG:D00088 PMID:2268561 11beta-hydrocortisone Wikipedia:Hydrocortisone PDBeChem:HCY hydrocortisone 362.45990 chebi_ontology C21H30O5 glucocorticoid 21-hydroxy steroid 11beta-hydroxy steroid anti-inflammatory drug 20-oxo steroid 3-oxo-Delta(4) steroid anti-asthmatic drug anti-allergic agent mouse metabolite human metabolite pregnane drug allergen