has role aristolochic acids CHEBI:194147 Organic heterotetracyclic compounds which are a group of nitro phenanthrene organic acids, naturally found in many kinds of plants, such as <em>Aristolochia</em> and <em>Asarum</em>, and widely cultivated in Asia.They are identified as a class 1 human carcinogen by the International Agency for Research on Cancer owing to their carcinogenicity and nephrotoxicity and can pose a significant hazard to food safety and human health. monocarboxylic acid C-nitro compound organic heterotetracyclic compound carcinogenic agent cyclic acetal nephrotoxin