has role steroid aldehyde primary alpha-hydroxy ketone mineralocorticoid aldosterone Beilstein:3224996 InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al PDBeChem:AS4 CAS:52-39-1 CHEBI:27584 ALDOSTERONE Drug_Central:111 LIPID_MAPS_instance:LMST02030026 PMID:10438974 [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO Aldosterone LINCS:LSM-42770 C21H28O5 aldosterone CHEBI:2563 A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al 360.44400 chebi_ontology 360.19367 Wikipedia:Aldosterone KEGG:C01780 Reaxys:3224996 DrugBank:DB04630 HMDB:HMDB0000037 PQSUYGKTWSAVDQ-ZVIOFETBSA-N CHEBI:40919 (+)-aldosterone CHEBI:22306 0 21-hydroxy steroid 11beta-hydroxy steroid 20-oxo steroid 18-oxo steroid 3-oxo-Delta(4) steroid C21-steroid hormone mouse metabolite human metabolite pregnane