has role independent continuant 3beta-hydroxy-Delta(5)-steroid geroprotector 17-oxo steroid dehydroepiandrosterone CHEBI:28689 3beta-Hydroxyandrost-5-en-17-one An androstanoid that is androst-5-ene substituted by a β-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands. 3beta-hydroxyandrost-5-en-17-one antidepressant analgesic hypoglycemic agent antineoplastic agent vasodilator agent antirheumatic drug antimalarial androgen androstanoid appetite enhancer anti-HIV agent mouse metabolite human metabolite