<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/ECTO?iri=http://purl.obolibrary.org/obo/CHEBI_28869"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/chebi/"
     xmlns:chebi="http://purl.obolibrary.org/obo/chebi#3"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchi"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/charge"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/smiles"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchikey"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/monoisotopicmass"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/formula"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/mass"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_147285 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_147285">
        <rdfs:label>EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_28384 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28384">
        <rdfs:label>vitamin K</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_28869 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28869">
        <rdfs:label>menadione</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_28384"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_84087"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35610"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_147285"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50733"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_48422"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasRelatedSynonym>menaquinone</oboInOwl:hasRelatedSynonym>
        <ns5:charge>0</ns5:charge>
        <oboInOwl:hasRelatedSynonym>3-methyl-1,4-naphthoquinone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:1697141</oboInOwl:hasDbXref>
        <ns5:formula>C11H8O2</ns5:formula>
        <oboInOwl:hasDbXref>MetaCyc:CPD-3766</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>2-methylnaphthoquinone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:32630491</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>2-methyl-1,4-naphthalenedione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:12665684</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>menaphthone</oboInOwl:hasRelatedSynonym>
        <ns5:inchikey>MJVAVZPDRWSRRC-UHFFFAOYSA-N</ns5:inchikey>
        <oboInOwl:hasDbXref>PMID:15722567</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2064595</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Chemspider:3915</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>2-methyl-1,4-naphthoquinone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:27304</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>PMID:19593550</oboInOwl:hasDbXref>
        <ns5:mass>172.183</ns5:mass>
        <oboInOwl:hasDbXref>CAS:58-27-5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:28166217</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>menaphthon</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Menadione</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>PMID:30119016</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:33800926</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9380028</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:8785182</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Aquinone</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000115>A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>menadione</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>PMID:19766112</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reaxys:1908453</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:2333843</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:46306</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>2-Methyl-1,4-naphthochinon</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:31701430</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31520616</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18698499</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:30609653</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1650428</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:VK3</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:32798378</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Aquakay</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>2-methylnaphthalene-1,4-dione</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>PMID:15265851</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C05377</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10433694</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Wikipedia:Menadione</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:31238027</oboInOwl:hasDbXref>
        <ns5:monoisotopicmass>172.05243</ns5:monoisotopicmass>
        <oboInOwl:hasRelatedSynonym>menaquinone 0</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:33227312</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:28869</oboInOwl:id>
        <ns5:smiles>CC1=CC(=O)C2=C(C=CC=C2)C1=O</ns5:smiles>
        <oboInOwl:hasDbXref>PMID:33901557</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16469140</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>menadion</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>vitamin K3</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>FooDB:FDB000953</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:33945810</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>LINCS:LSM-3755</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9010592</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15052609</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:13779073</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:1857739</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:34040527</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:3083821</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>MENADIONE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>PMID:16109308</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00170</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:11372776</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>KEGG:D02335</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0001892</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:6747</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>Hemodal</oboInOwl:hasRelatedSynonym>
        <ns5:inchi>InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3</ns5:inchi>
        <oboInOwl:hasDbXref>Drug_Central:1683</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:16140270</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12895502</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15613473</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Kappaxin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cdno.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35610 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35610">
        <rdfs:label>antineoplastic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_48422 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48422">
        <rdfs:label>angiogenesis inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_50733 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50733">
        <rdfs:label>nutraceutical</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_84087 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_84087">
        <rdfs:label>human urinary metabolite</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



