<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/ECTO?iri=http://purl.obolibrary.org/obo/CHEBI_28918"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/chebi/"
     xmlns:chebi2="http://purl.obolibrary.org/obo/chebi#"
     xmlns:chebi="http://purl.obolibrary.org/obo/chebi#3"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchi"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/charge"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/smiles"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchikey"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/monoisotopicmass"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/formula"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/mass"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of"/>
    


    <!-- http://purl.obolibrary.org/obo/chebi#is_enantiomer_of -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/chebi#is_enantiomer_of"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_194548 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_194548">
        <rdfs:label>4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24621 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24621">
        <rdfs:label>hormone</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_28918 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_28918">
        <rdfs:label>(R)-adrenaline</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_194548"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24621"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50513"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35524"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/chebi#is_enantiomer_of"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_40751"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_71406"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_75771"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35522"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_50514"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35620"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35523"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35569"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasRelatedSynonym>epinefrina</oboInOwl:hasRelatedSynonym>
        <ns5:inchi>InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1</ns5:inchi>
        <oboInOwl:hasRelatedSynonym>(R)-(-)-Epirenamine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Epinephrin</oboInOwl:hasRelatedSynonym>
        <ns5:mass>183.20440</ns5:mass>
        <oboInOwl:hasDbXref>KNApSAcK:C00029643</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:1028</oboInOwl:hasDbXref>
        <ns5:charge>0</ns5:charge>
        <oboInOwl:hasDbXref>PMID:21963816</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MetaCyc:L-EPINEPHRINE</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22425731</oboInOwl:hasDbXref>
        <ns5:formula>C9H13NO3</ns5:formula>
        <oboInOwl:hasRelatedSynonym>(-)-(R)-epinephrine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:18325983</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22115931</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22898765</oboInOwl:hasDbXref>
        <ns5:monoisotopicmass>183.08954</ns5:monoisotopicmass>
        <ns4:IAO_0000115>The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the &#39;fight-or-flight&#39; response.</ns4:IAO_0000115>
        <oboInOwl:hasRelatedSynonym>(R)-(-)-adrenaline</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:23066296</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22623754</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>KEGG:C00788</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>epinephrinum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:22429969</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>adrenaline</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>L-Adrenaline</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:22905594</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:23928</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Wikipedia:Epinephrine</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(R)-(-)-Adnephrine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(R)-(-)-Epinephrine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <ns5:inchikey>UCTWMZQNUQWSLP-VIFPVBQESA-N</ns5:inchikey>
        <oboInOwl:hasRelatedSynonym>Adrenalin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:22895980</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Epipen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reaxys:2368277</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Epipen JR</oboInOwl:hasRelatedSynonym>
        <ns5:smiles>CNC[C@H](O)c1ccc(O)c(O)c1</ns5:smiles>
        <oboInOwl:hasRelatedSynonym>(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>levoepinephrine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:1942</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>PMID:23185846</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(-)-adrenaline</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>HMDB:HMDB0000068</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>epinephrine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:23130169</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22940899</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB00668</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Primatene</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(R)-(-)-Adrenaline</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:22405854</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:22569014</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29438107</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CAS:51-43-4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23164182</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00095</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Beilstein:2368277</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:28918</oboInOwl:id>
        <oboInOwl:hasDbXref>PMID:22826982</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35522 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35522">
        <rdfs:label>beta-adrenergic agonist</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35523 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35523">
        <rdfs:label>bronchodilator agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35524 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35524">
        <rdfs:label>sympathomimetic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35569 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35569">
        <rdfs:label>alpha-adrenergic agonist</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35620 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35620">
        <rdfs:label>vasodilator agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_40751 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_40751">
        <rdfs:label>(S)-adrenaline</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_50513 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50513">
        <rdfs:label>mydriatic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_50514 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50514">
        <rdfs:label>vasoconstrictor agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_71406 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_71406">
        <rdfs:label>(R)-adrenaline(1+)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_75771 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_75771">
        <rdfs:label>mouse metabolite</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



