<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/ECTO?iri=http://purl.obolibrary.org/obo/CHEBI_34892"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/chebi/"
     xmlns:chebi="http://purl.obolibrary.org/obo/chebi#3"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchi"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/charge"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/smiles"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/inchikey"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/monoisotopicmass"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/formula"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/chebi/mass"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_22715 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_22715">
        <rdfs:label>benzimidazoles</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_23003 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23003">
        <rdfs:label>carbamate ester</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_26961 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_26961">
        <rdfs:label>thiophenes</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_34892 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_34892">
        <rdfs:label>nocodazole</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_22715"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23003"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_26961"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_76224"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35610"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_61951"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:id>CHEBI:34892</oboInOwl:id>
        <oboInOwl:hasDbXref>PMID:7284368</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>nocodazolum</oboInOwl:hasRelatedSynonym>
        <ns4:IAO_0000115>A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>PMID:20399776</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:23869451</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>LINCS:LSM-2260</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>nocodazole</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>R 17934</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Beilstein:1085978</oboInOwl:hasDbXref>
        <ns5:smiles>COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1cccs1</ns5:smiles>
        <oboInOwl:hasDbXref>PMID:518692</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>methyl N-(5-thenoyl-2-benzimidazolyl)carbamate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:7199049</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C13719</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>DrugBank:DB08313</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>KEGG:D05197</oboInOwl:hasDbXref>
        <ns5:mass>301.32000</ns5:mass>
        <oboInOwl:hasDbXref>PMID:22002881</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PDBeChem:NZO</oboInOwl:hasDbXref>
        <ns5:formula>C14H11N3O3S</ns5:formula>
        <oboInOwl:hasDbXref>PMID:11679255</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>R17,934</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:7344613</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamic acid methyl ester</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>N-(5-(2-thenoyl)-2-benzimidazolyl)carbamic acid methyl ester</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:6384770</oboInOwl:hasDbXref>
        <ns5:inchikey>KYRVNWMVYQXFEU-UHFFFAOYSA-N</ns5:inchikey>
        <ns5:monoisotopicmass>301.05211</ns5:monoisotopicmass>
        <ns5:charge>0</ns5:charge>
        <oboInOwl:hasRelatedSynonym>N-(5-(2-thienoyl)-2-benzimidazolyl)carbamic acid methyl ester</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Reaxys:1085978</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>nocodazol</oboInOwl:hasRelatedSynonym>
        <ns5:inchi>InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)</ns5:inchi>
        <oboInOwl:hasDbXref>CAS:31430-18-9</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>oncodazole</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>R-17934</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Nocodazole</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35610 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35610">
        <rdfs:label>antineoplastic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_61951 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_61951">
        <rdfs:label>microtubule-destabilising agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_76224 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_76224">
        <rdfs:label>aromatic ketone</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



