has role benzodiazepine xenobiotic organochlorine compound organochlorine compound clozapine chebi_ontology InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 HMDB:HMDB0014507 N1=C(C2=CC=CC=C2NC3=CC=C(C=C13)Cl)N4CCN(CC4)C CAS:5786-21-0 QZUDBNBUXVUHMW-UHFFFAOYSA-N Patent:NL293201 Reaxys:764984 KEGG:C06924 A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia. 0 Patent:US3539573 clozapina clozapine clozapinum PMID:24219174 KEGG:D00283 Drug_Central:722 Wikipedia:Clozapine C18H19ClN4 PMID:18690109 PMID:18766167 DrugBank:DB00363 Clozapin 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Beilstein:0764984 PMID:20825390 Patent:FR1334944 CHEBI:3766 Clozapine 326.12982 326.824 adrenergic antagonist histamine antagonist N-arylpiperazine N-methylpiperazine serotonergic antagonist dopaminergic antagonist muscarinic antagonist second generation antipsychotic GABA antagonist EC 3.4.21.26 (prolyl oligopeptidase) inhibitor environmental contaminant