has role is deprotonated form of independent continuant geroprotector fasudil(1+) isoquinolines vasodilator agent antihypertensive agent calcium channel blocker fasudil CHEBI:43871 An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia. N-sulfonyldiazepane EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor neuroprotective agent nootropic agent