has role carboxamidine dicarboxylic acid monoamide azetidines melagatran DKWNMCUOEDMMIN-PKOBYXMFSA-N N-[(1R)-2-{(2S)-2-[(4-carbamimidoylbenzyl)carbamoyl]azetidin-1-yl}-1-cyclohexyl-2-oxoethyl]glycine A member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. melagatranum PMID:9459334 429.23760 PMID:12846595 melagatran PMID:22546231 0 PMID:10102460 N-((R)-(((2S)-2-((-p-amidobenzyl)carbamoyl)-1-azetidinyl)carbonyl)cyclohexylmethyl)glycine CHEBI:43966 KEGG:D07143 Reaxys:8090770 [H][C@]1(CCN1C(=O)[C@H](NCC(O)=O)C1CCCCC1)C(=O)NCc1ccc(cc1)C(N)=N C22H31N5O4 PMID:16106594 PMID:28338626 PDBeChem:MEL PMID:15487959 429.51260 CAS:159776-70-2 chebi_ontology PMID:13680847 PMID:11060733 CHEBI:73114 PMID:16767816 PMID:16123912 InChI=1S/C22H31N5O4/c23-20(24)16-8-6-14(7-9-16)12-26-21(30)17-10-11-27(17)22(31)19(25-13-18(28)29)15-4-2-1-3-5-15/h6-9,15,17,19,25H,1-5,10-13H2,(H3,23,24)(H,26,30)(H,28,29)/t17-,19+/m0/s1 anticoagulant secondary amino compound serine protease inhibitor EC 3.4.21.5 (thrombin) inhibitor non-proteinogenic alpha-amino acid