has role L-glutamic acid pteridines monocarboxylic acid amide antineoplastic agent dicarboxylic acid immunosuppressive agent antirheumatic drug methotrexate FBOZXECLQNJBKD-ZDUSSCGKSA-N DrugBank:DB00563 0 CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid Patent:US2512572 CAS:59-05-2 LINCS:LSM-5690 CHEBI:6837 Methotrexate 4-amino-N(10)-methylpteroylglutamic acid MTX METHOTREXATE InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1 PDBeChem:MTX KEGG:C01937 methotrexatum 454.17132 4-amino-10-methylfolic acid chebi_ontology C20H22N8O5 Emtexate Wikipedia:Methotrexate N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid CHEBI:44183 Rheumatrex CHEBI:44185 Trexall Beilstein:70669 Ledertrexate metotrexato methotrexate KEGG:D00142 454.43960 Drug_Central:1751 dermatologic drug methotrexate(1-) EC 1.5.1.3 (dihydrofolate reductase) inhibitor abortifacient DNA synthesis inhibitor