has role antimetabolite antineoplastic agent hydroxyurea KEGG:C07044 VSNHCAURESNICA-UHFFFAOYSA-N NC(=O)NO carbamohydroxamic acid N-hydroxyurea InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4) chebi_ontology Hydroxyharnstoff A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. KEGG:D00341 carbamyl hydroxamate DrugBank:DB01005 MetaCyc:HYDROXY-UREA CAS:127-07-1 hydrea hidroxicarbamida N-carbamoylhydroxylamine N-HYDROXYUREA PMID:15772364 Drug_Central:1399 hydroxycarbamide Reaxys:1741548 hydroxycarbamidum Patent:US2705727 CHEBI:44423 carbamohydroximic acid CHEBI:44420 Beilstein:1741548 PMID:9271088 PMID:11298103 CHEBI:5816 PMID:11365149 PMID:11364534 Hydroxycarbamide 76.02728 76.05474 HMDB:HMDB0015140 0 PMID:14988684 PMID:11285159 Hydroxycarbamid PMID:23643402 oxyurea hydroxyurea CH4N2O2 Gmelin:130423 Hydroxyurea PMID:15994344 Wikipedia:Hydroxyurea PMID:11391710 PDBeChem:NHY PMID:22983419 PMID:23696560 PMID:23318979 PMID:16356682 carbamoyl oxime PMID:12107454 ureas radical scavenger immunomodulator genotoxin teratogenic agent DNA synthesis inhibitor one-carbon compound antimitotic EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor