has role ethanolamines ethylenediamine derivative antitubercular agent xenobiotic ethambutol An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (<i>S</i>,<i>S</i>-configuration). It is a bacteriostatic antimycobacterial drug, effective against <em>Mycobacterium tuberculosis</em> and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of <em>M. tuberculosis</em> are readily produced if ethambutol is used alone. CHEBI:4877 secondary amino compound anti-inflammatory agent environmental contaminant