has role 17-oxo steroid androstane antineoplastic agent xenobiotic exemestane DrugBank:DB00990 Exemestane PMID:10882163 exemestane chebi_ontology Wikipedia:Exemestane Reaxys:6609645 exemestanum exemestano KEGG:D00963 Drug_Central:1122 CHEBI:4953 InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1 296.40340 296.17763 [H][C@@]12CC(=C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=O)CC[C@@]21[H] BFYIZQONLCFLEV-DAELLWKTSA-N A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer. KEGG:C08162 6-methylideneandrosta-1,4-diene-3,17-dione C20H24O2 0 6-methyleneandrosta-1,4-diene-3,17-dione CAS:107868-30-4 EC 1.14.14.14 (aromatase) inhibitor 3-oxo-Delta(1),Delta(4)-steroid environmental contaminant