has role lignan antineoplastic agent keratolytic drug podophyllotoxin PMID:15803102 0 PMID:23798883 DrugBank:DB01179 YJGVMLPVUAXIQN-XVVDYKMHSA-N Podophyllotoxin PDBeChem:POD Condylox KEGG:D05529 9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE PMID:23161544 414.13147 PMID:8112825 chebi_ontology KEGG:C10874 CAS:518-28-5 C22H22O8 LINCS:LSM-3055 HMDB:HMDB0031452 KNApSAcK:C00000610 CHEBI:45070 PMID:22621772 Wikipedia:Podophyllotoxin An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts. [H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1[C@@H]2O Drug_Central:3481 (-)-podophyllotoxin Podofilox 414.40530 Podophyllinic acid lactone CHEBI:8280 Podophyllotoxin 7 (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one PPT Reaxys:99163 CHEBI:50305 InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1 furonaphthodioxole microtubule-destabilising agent plant metabolite