has role has functional parent independent continuant antiviral agent antifibrotic agent purine ribonucleoside monophosphate antimetabolite antineoplastic agent immunosuppressive agent organofluorine compound purine arabinonucleoside monophosphate prodrug DNA synthesis inhibitor nucleoside analogue fludarabine phosphate CHEBI:63599 A purine arabinonucleoside monophosphate having 2-fluoroadenine as the nucleobase. A prodrug, it is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. Once incorporated into DNA, 2-fluoro-ara-ATP functions as a DNA chain terminator. It is used for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to, or whose disease has progressed during, treatment with at least one standard alkylating-agent containing regimenas. 2-fluoroadenine anti-anaemic agent