has role is protonated form of has functional parent renoprotective agent antifibrotic agent metabolite antitubercular agent carboxylic ester hypoglycemic agent antineoplastic agent antihypertensive agent secondary alcohol xenobiotic immunosuppressive agent carbocyclic fatty acid antirheumatic drug hydroxy monocarboxylic acid carbobicyclic compound (S)-2-methylbutyric acid 3-hydroxy carboxylic acid pravastatin CHEBI:63618 A carboxylic ester resulting from the formal condensation of (<i>S</i>)-2-methylbutyric acid with the hydroxy group adjacent to the ring junction of (3<i>R</i>,5<i>R</i>)-7-[(1<i>S</i>,2<i>S</i>,6<i>S</i>,8<i>S</i>,8a<i>R</i>)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. Derived from microbial transformation of mevastatin, pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). The sodium salt is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin. (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid pravastatin(1-) anti-HIV agent environmental contaminant statin (semi-synthetic)