has role ethanolamines sulfonamide beta-adrenergic antagonist secondary alcohol xenobiotic anti-arrhythmia drug secondary amino compound sotalol KEGG:C07309 sotalol PMID:20562595 InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 272.11946 beta-cardone sotalolum LINCS:LSM-1465 chebi_ontology CHEBI:63622 CAS:3930-20-9 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide Reaxys:2380820 A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias. DrugBank:DB00489 Wikipedia:Sotalol CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide PMID:21854895 ZBMZVLHSJCTVON-UHFFFAOYSA-N Sotalol Drug_Central:2464 KEGG:D08525 HMDB:HMDB0014632 CHEBI:9206 272.36400 C12H20N2O3S 0 PMID:21553267 sotalol(1+) environmental contaminant