has role is enantiomer of renoprotective agent antineoplastic agent pyrazolopyridine biomarker EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor crizotinib A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has <i>R</i> configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) CHEBI:64310 ent-crizotinib 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine