has role is deprotonated form of has parent hydride primary aliphatic amine antidepressant anxiolytic drug antipsychotic agent analgesic antineoplastic agent immunosuppressive agent antiglaucoma drug adamantane antiparkinson drug dopaminergic agent adamantanes NMDA receptor antagonist racemate neuroprotective agent memantine CHEBI:64312 A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. memantinium(1+) anti-obesity agent