has role nitrile antiviral agent renoprotective agent antineoplastic agent antirheumatic drug pyrrolopyrimidine N-acylpiperidine antipsoriatic tertiary amino compound ophthalmology drug anti-inflammatory agent antileishmanial agent tofacitinib CHEBI:71200 A pyrrolopyrimidine that is pyrrolo[2,3-<em>d</em>]pyrimidine substituted at position 4 by an <em>N</em>-methyl,<em>N</em>-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis. vulnerary EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor