C-glycosyl compound carbohydrate-containing antibiotic o-orsellinic acid fatty acid ester 2-benzofurans papulacandin CHEBI:72596 chebi_ontology PMID:12374387 PMID:324958 PMID:7649857 PMID:6360972 Any of the carbohydrate-containing antibiotic compounds obtained from the deuteromycetous fungus Papularia sphaerosperma and generally consisting of o-orsellinic acid linked via a spirocyclic structure to a lactose moiety with two different side-chains: a shorter fatty-acid chain at the O-(6') position and a longer side-chain at the O-(3) position of the glucose moiety. Papulacandin D, the simplest member of the papulacandin family, lacks the O-(6'-acyl-beta-galactoside) at the O-(4) position of the glucose residue. The papulacandins show potent antifungal activity against Candida albicans, Geotrichum lactis, Saccharomyces cerevisiae, and Pneumocytis carinii, but are inactive against filamentous fungi, bacteria, and protazoa. PMID:7440418 papulacandins PMID:3839230 PMID:20711516 PMID:3839234 PMID:8468238 spiroketal