has role metabolite opioid analgesic adrenergic uptake inhibitor serotonergic antagonist muscarinic antagonist nicotinic antagonist serotonin uptake inhibitor antitussive mu-opioid receptor agonist kappa-opioid receptor agonist NMDA receptor antagonist delta-opioid receptor agonist capsaicin receptor antagonist 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol (R,R)-tramadol KEGG:D08623 263.37520 COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C VSDB:3008 CAS:27203-92-5 C16H25NO2 chebi_ontology CHEBI:75725 TVYLLZQTGLZFBW-ZBFHGGJFSA-N LINCS:LSM-5221 (+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol Reaxys:9590387 InChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1 A 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. (+)-tramadol Wikipedia:Tramadol KEGG:C07153 (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol 0 CAS:123154-38-1 263.18853 (S,S)-tramadol (R,R)-tramadol(1+)