has role tertiary carboxamide acrylamides antiviral agent aromatic amine antineoplastic agent aromatic ether pyrazolopyrimidine N-acylpiperidine anti-anaemic agent ibrutinib CHEBI:76612 A member of the class of acrylamides that is (3<i>R</i>)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-<em>d</em>]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies. EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor