has role is deprotonated form of antiviral agent antifibrotic agent methyl ester aromatic amine antineoplastic agent oxindoles tyrosine kinase inhibitor N-alkylpiperazine indolyl carboxylic acid enamine angiogenesis inhibitor aromatic ester aromatic amide fibroblast growth factor receptor antagonist vascular endothelial growth factor receptor antagonist nintedanib A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer. CHEBI:85164 nintedanib(1+)