has role steroid lactone diuretic antihypertensive agent xenobiotic oxaspiro compound 3-oxo-Delta(4) steroid aldosterone antagonist thioester environmental contaminant spironolactone 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone 0 Spironolactone espironolactona spironolactone spironolattone DrugBank:DB00421 InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1 Wikipedia:Spironolactone A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7. chebi_ontology PDBeChem:SNL LXMSZDCAJNLERA-ZHYRCANASA-N KEGG:D00443 CHEBI:9241 spironolactonum 416.57448 Beilstein:57767 Drug_Central:2475 CAS:52-01-7 KEGG:C07310 C24H32O4S HMDB:HMDB0014565 Patent:US3013012 PMID:11300427 Reaxys:57767 CHEBI:45692 416.20213 [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]33CCC(=O)O3)[C@]1([H])[C@@H](CC1=CC(=O)CC[C@]21C)SC(C)=O