has part has part has_part has role opioid analgesic adrenergic uptake inhibitor xenobiotic serotonergic antagonist muscarinic antagonist nicotinic antagonist serotonin uptake inhibitor antitussive mu-opioid receptor agonist kappa-opioid receptor agonist NMDA receptor antagonist racemate delta-opioid receptor agonist capsaicin receptor antagonist (R,R)-tramadol (S,S)-tramadol tramadol(1+) environmental contaminant tramadol U-26225A PMID:23098678 PMID:23543914 PMID:23962470 PMID:25219922 PMID:23907474 E-265 (+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol C16H25NO2 CG-315E PMID:23031839 tramadolum HMDB:HMDB0014339 263.37520 Patent:GB997399 PMID:23292128 CAS:27203-92-5 PMID:22674657 PMID:22943675 tramadol A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia. PMID:23433451 PMID:23328338 PMID:23822079 KEGG:C07153 PMID:23840975 PMID:23668411 rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Reaxys:2943832 PMID:23099620 Patent:US3652589 PMID:22964800 CHEBI:9648 DrugBank:DB00193 PMID:23773348 chebi_ontology KEGG:D08623 Wikipedia:Tramadol PMID:23102445 PMID:23872384 PMID:23825758 0 263.18853 PMID:23843224 PMID:23061925 PMID:23756535 PMID:23145962 PMID:23755929 PMID:24014188 PMID:23095734