has primary output indoles biosynthetic process heterocycle biosynthetic process aromatic compound biosynthetic process indole-containing compound metabolic process indole-containing compound biosynthetic process indole derivative biosynthesis The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. biological_process GO:0042435 indole-containing compound biosynthesis indole-containing compound anabolism indole-containing compound formation indole-containing compound synthesis indole derivative biosynthetic process cellular nitrogen compound biosynthetic process organic cyclic compound biosynthetic process organonitrogen compound biosynthetic process