therapeutic uses has role chemical entity EC 3.1.1.8 (cholinesterase) inhibitor pharmacotherapy antidementia agent therapy cholinesteriase inhibitor therapy They are a group of drugs that block the normal breakdown of acetylcholine (ACh) into acetate and choline and thereby increase both the levels and duration of actions of acetylcholine found in the central and peripheral nervous system. treatment with EC 3.1.1.8 (cholinesterase) inhibitor cholinesterase inhibitor drug treatment cholinesterase inhibitor medication therapy CHEBI:37733 Neurogenerative diseases such as Alzheimer disease, Parkinson disease, and Lewy body dementia are indications for cholinesterase inhibitor therapy. enzyme inhibitor agent therapy