pharmacotherapy NSAID therapy treatment with non-steroidal anti-inflammatory drug treatment with NSAID medication treatment with non-steroidal anti-inflammatory medication non-steroidal anti-inflammatory medication treatment treatment with NSAID therapy CHEBI:35475 treatment with NSAID drug Treatment with an anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.