Substance Abuse Individual Behavior Substance Abuse CTRP C18272 C0740858 substance abuse The use of illegal drugs or the use of prescription or over-the-counter drugs or alcohol for purposes other than those for which they are meant to be used, or in excessive amounts. Substance abuse may lead to social, physical, emotional, and job-related problems. Substance Abuse Maladaptive pattern of drug or alcohol use that may lead to social, occupational, psychological, or physical problems. Substance Abuse Substance_Abuse Personal Behavior