has topic Nucleic acid feature detection CpG island and isochore detection Find CpG rich regions in a nucleotide sequence or isochores in genome sequences. CpG island and isochores rendering beta12orEarlier An isochore is long region (> 3 KB) of DNA with very uniform GC content, in contrast to the rest of the genome. Isochores tend tends to have more genes, higher local melting or denaturation temperatures, and different flexibility. Methods might calculate fractional GC content or variation of GC content, predict methylation status of CpG islands etc. This includes methods that visualise CpG rich regions in a nucleotide sequence, for example plot isochores in a genome sequence. CpG island and isochores detection Sequence composition, complexity and repeats