Sequencing quality control Read pre-processing 1.1 For example process paired end reads to trim low quality ends remove short sequences, identify sequence inserts, detect chimeric reads, or remove low quality sequences including vector, adaptor, low complexity and contaminant sequences. Sequences might come from genomic DNA library, EST libraries, SSH library and so on. Pre-process sequence reads to ensure (or improve) quality and reliability. Sequence read pre-processing Sequence read processing