has_role norfloxacin 0 319.13322 319.336 KEGG COMPOUND:70458-96-7 "CAS Registry Number" cas:70458-96-7 Patent:DE2840910 "Patent" NFLX reaxys:567897 CiteXplore:6454381 "PubMed citation" DrugBank:DB01059 "DrugBank" MESH:D009643 vsdb:1831 chebi_ontology drugbank:DB01059 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid patent:US4292317 patent:BE863429 norfloxacin SNOMEDCT:49485009 Gmelin:1576626 "Gmelin Registry Number" ChEMBL:100246 "ChEMBL COMPOUND" pubmed:3908074 CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 CiteXplore:3317294 "PubMed citation" CiteXplore:3908074 "PubMed citation" ChemIDplus:70458-96-7 "CAS Registry Number" pubmed:3317294 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid pubmed:6234465 C16H18FN3O3 pubmed:6211142 A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. kegg.compound:C06687 SNOMEDCT:387271008 CiteXplore:6211142 "PubMed citation" 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure drugcentral:1967 Patent:US4292317 "Patent" KEGG DRUG:D00210 "KEGG DRUG" CHEBI:100246 norfloxacinum 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid Patent:BE863429 "Patent" norfloxacino InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23) Patent:US4146719 "Patent" pubmed:6461606 NCIt:C47638 norfloxacine CiteXplore:6234465 "PubMed citation" kegg.drug:D00210 KEGG COMPOUND:C06687 "KEGG COMPOUND" Beilstein:567897 "Beilstein Registry Number" pubmed:6224685 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid Wikipedia:Norfloxacin "Wikipedia" CiteXplore:6224685 "PubMed citation" lincs.smallmolecule:LSM-5286 patent:US4146719 CiteXplore:6461606 "PubMed citation" wikipedia.en:Norfloxacin patent:DE2840910 OGJPXUAPXNRGGI-UHFFFAOYSA-N CHEBI:7629 gmelin:1576626 pubmed:6454381 hmdb:HMDB0015192 organic heterocyclic compound carboxylic acid antibacterial drug DNA synthesis inhibitor