mycophenolic acid 0 320.12599 320.341 mycophenolic acid wikipedia.en:Mycophenolic_acid kegg.drug:D05096 (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid A member of the class of 2-benzofurans that is 2-benzofuran-1(3<em>H</em>)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2<i>E</i>)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by <em>Penicillium brevi-compactum, P. stoloniferum, P. echinulatum</em> and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases. patent:US4753935 pubmed:19689217 Micofenolico acido drugcentral:1860 pubmed:15470161 pubmed:17498396 drugbank:DB01024 acide mycophenolique reaxys:318158 CHEBI:43973 pubmed:16629948 (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid pubmed:16640327 pubmed:18611107 HPNSFSBZBAHARI-RUDMXATFSA-N COc1c(C)c2c(c(O)c1C/C=C(C)CCC(=O)O)C(=O)OC2 pubmed:18996104 acido micofenolico C17H20O6 pubmed:11272311 pubmed:18194117 pubmed:17482154 cas:24280-93-1 pdb-ccd:MOA acidum mycophenolicum InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+ chebi_ontology Mycophenolsaeure Mycophenolate (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid CHEBI:168396 organic heterocyclic compound carboxylic acid phenols