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    <!-- http://purl.obolibrary.org/obo/CHEBI_16899 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16899">
        <rdfs:label>D-mannitol</rdfs:label>
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        <oboInOwl:hasDbXref>knapsack:C00001165</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>wikipedia.en:Mannitol</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>E 421</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:6686</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>D-mannitol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>pubmed:16854081</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:17983214</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Mannitol</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>The &lt;small&gt;D&lt;/small&gt;-enantiomer of mannitol.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>MESH:D008353</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>D-Mannitol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>drugcentral:935</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Osmitrol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>mannitol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIt:C625</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:25108762</oboInOwl:hasDbXref>
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        <oboInOwl:hasRelatedSynonym>(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>dulcite</oboInOwl:hasRelatedSynonym>
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        <oboInOwl:hasDbXref>kegg.compound:C00392</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>pubmed:15658873</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:16899</oboInOwl:id>
        <ns5:wurcs_representation>WURCS=2.0/1,1,0/[h1122h]/1/</ns5:wurcs_representation>
        <oboInOwl:hasRelatedSynonym>mannite</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:17973471</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>E-421</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:17420133</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>drugbank:DB00742</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:17336832</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:18220330</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:24643482</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>reaxys:1721898</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>E421</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:17979222</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>pdb-ccd:MTL</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>mannitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:21050</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>pubmed:11784135</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>metacyc.compound:MANNITOL</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:22770225</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:44192</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>SNOMEDCT:30761007</oboInOwl:hasDbXref>
        <ns5:inchi_string>InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1</ns5:inchi_string>
        <oboInOwl:hasRelatedSynonym>Mannitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:15863337</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>D-(-)-Mannitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>cas:69-65-8</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>manna sugar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>D-mannitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:12996</oboInOwl:hasAlternativeId>
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        <oboInOwl:hasDbXref>gmelin:83161</oboInOwl:hasDbXref>
        <ns5:smiles_string>OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO</ns5:smiles_string>
        <oboInOwl:hasDbXref>pubmed:17827020</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:16901854</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:130180</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>pubmed:18207412</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>D-Mannitol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>SNOMEDCT:387168006</oboInOwl:hasDbXref>
        <ns5:generalized_empirical_formula>C6H14O6</ns5:generalized_empirical_formula>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_23366 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23366">
        <rdfs:label>compatible osmolytes</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_29864 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_29864">
        <rdfs:label>mannitol</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_50504 -->

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        <rdfs:label>osmotic diuretic</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_50505 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50505">
        <rdfs:label>sweetening agent</rdfs:label>
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