<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/EFO?iri=http://purl.obolibrary.org/obo/CHEBI_17303"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="https://w3id.org/chemrof/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:obo="http://purl.obolibrary.org/obo#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:efo="http://www.ebi.ac.uk/efo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="https://w3id.org/chemrof/inchi_key_string"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/smiles_string"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/charge"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/generalized_empirical_formula"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/mass"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/inchi_string"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/monoisotopic_mass"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo#has_role -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo#has_role">
        <rdfs:label>has_role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_17303 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17303">
        <rdfs:label>morphine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24532"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                <someValuesFrom rdf:resource="http://www.ebi.ac.uk/efo/EFO_0001899"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns5:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns5:charge>
        <ns5:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">285.13649</ns5:monoisotopic_mass>
        <ns5:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">285.343</ns5:mass>
        <ns5:inchi_key_string>BQJCRHHNABKAKU-KBQPJGBKSA-N</ns5:inchi_key_string>
        <oboInOwl:hasDbXref>pubmed:24096538</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:373529000</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id>CHEBI:17303</oboInOwl:id>
        <oboInOwl:hasDbXref>pubmed:23988259</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:14622</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>pubmed:21061062</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pdb-ccd:MOI</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:27866460</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>metacyc.compound:MORPHINE</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:17171884</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>morphinum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:27735107</oboInOwl:hasDbXref>
        <ns5:generalized_empirical_formula>C17H19NO3</ns5:generalized_empirical_formula>
        <oboInOwl:hasDbXref>reaxys:93704</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:15019787</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:44202</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>pubmed:23292329</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>morphium</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:27815868</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:9231550</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>kegg.compound:C01516</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Morphine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>drugcentral:1845</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:12593758</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIt:C62051</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT:73572009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23927484</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:17667569</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:23325235</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>wikipedia.en:Morphine</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:25419</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>Morphin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:29368335</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:19371311</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>morfina</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>vsdb:2982</oboInOwl:hasDbXref>
        <ns5:smiles_string>[H][C@@]12C=C[C@H](O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(C)[C@@H]2C5</ns5:smiles_string>
        <oboInOwl:hasExactSynonym>17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:7001</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>cas:57-27-2</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pdb:1Q0Y</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(-)-morphine</oboInOwl:hasRelatedSynonym>
        <ns4:IAO_0000115>A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in &lt;em&gt;Papaver somniferum&lt;/em&gt; (the opium poppy).</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>pubmed:23555556</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:20071451</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>kegg.drug:D08233</oboInOwl:hasDbXref>
        <ns5:inchi_string>InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1</ns5:inchi_string>
        <oboInOwl:hasRelatedSynonym>(5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Morphia</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>drugbank:DB00295</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009020</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>pubmed:24306419</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>knapsack:C00001889</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi/3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24532 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24532">
        <rdfs:label>organic heterocyclic compound</rdfs:label>
    </Class>
    


    <!-- http://www.ebi.ac.uk/efo/EFO_0001899 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0001899">
        <rdfs:label>drug role</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



