<?xml version="1.0"?>
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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="https://w3id.org/chemrof/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:obo="http://purl.obolibrary.org/obo#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
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     xmlns:efo="http://www.ebi.ac.uk/efo/">
    


    <!-- 
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    <AnnotationProperty rdf:about="https://w3id.org/chemrof/inchi_key_string"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/smiles_string"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/charge"/>
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/generalized_empirical_formula"/>
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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="https://w3id.org/chemrof/mass"/>
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    <!-- http://purl.obolibrary.org/obo#has_role -->

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        <rdfs:label>has_role</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_23965 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23965">
        <rdfs:label>estradiol</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_33853"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35341"/>
        <rdfs:subClassOf>
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                <onProperty rdf:resource="http://purl.obolibrary.org/obo#has_role"/>
                <someValuesFrom rdf:resource="http://www.ebi.ac.uk/efo/EFO_0001824"/>
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        </rdfs:subClassOf>
        <ns5:charge rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">0</ns5:charge>
        <ns5:monoisotopic_mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">272.17763</ns5:monoisotopic_mass>
        <ns5:mass rdf:datatype="http://www.w3.org/2001/XMLSchema#decimal">272.388</ns5:mass>
        <ns5:generalized_empirical_formula>C18H24O2</ns5:generalized_empirical_formula>
        <oboInOwl:hasDbXref>pubmed:10696569</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>oestradiol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>wikipedia.en:Estradiol</oboInOwl:hasDbXref>
        <ns5:inchi_key_string>VOXZDWNPVJITMN-WKUFJEKOSA-N</ns5:inchi_key_string>
        <ns5:smiles_string>[H][C@@]12CCc3cc(O)ccc3[C@@]1([H])CC[C@]1(C)C(O)CC[C@@]21[H]</ns5:smiles_string>
        <oboInOwl:id>CHEBI:23965</oboInOwl:id>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>MESH:D004958</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>pubmed:24084694</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>estra-1,3,5(10)-triene-3,17-diol</oboInOwl:hasRelatedSynonym>
        <ns5:inchi_string>InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1</ns5:inchi_string>
        <oboInOwl:hasDbXref>SNOMEDCT:126172005</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:42364</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>NCIt:C2295</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>estra-1,3,5(10)-triene-3,17-diol</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.</ns4:IAO_0000115>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi/3_STAR"/>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_33853 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_33853">
        <rdfs:label>phenols</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35341 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35341">
        <rdfs:label>steroid</rdfs:label>
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    <!-- http://www.ebi.ac.uk/efo/EFO_0001824 -->

    <Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0001824">
        <rdfs:label>hormone role</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



