has_role steroid hormone aldosterone 0 360.19367 360.45 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al Aldosterone cas:52-39-1 wikipedia.en:Aldosterone CHEBI:27584 PQSUYGKTWSAVDQ-ZVIOFETBSA-N InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 pubmed:10438974 [H][C@@]12CC[C@]([H])(C(=O)CO)[C@@]1(C=O)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@@]21C MESH:D000450 reaxys:3224996 CHEBI:2563 A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. SNOMEDCT:42605004 drugcentral:111 drugbank:DB04630 (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al chebi_ontology kegg.compound:C01780 pdb-ccd:AS4 ALDOSTERONE 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al CHEBI:40919 (+)-aldosterone lipidmaps:LMST02030026 NCIt:C219 hmdb:HMDB0000037 CHEBI:22306 C21H28O5 lincs.smallmolecule:LSM-42770 aldosterone