organic heterocyclic compound aristolochic acid A 0 341.05355 341.275 Aristolochic acid I aristolochic acid-I wikipedia.en:Aristolochic_acid pubmed:21719716 CiteXplore:21719716 COc1cccc2c1cc([N+](=O)[O-])c1c(C(=O)O)cc3c(c12)OCO3 ChemIDplus:313-67-7 Reaxys:345159 reaxys:345159 CHEBI:2825 pubmed:21558304 aristolochic acid A MESH:C000228 ChEMBL:250437 CiteXplore:21558304 3,4-methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid C17H11NO7 lincs.smallmolecule:LSM-2373 pubmed:22071594 8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid CiteXplore:22126455 8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid knapsack:C00027516 pubmed:22118289 pubmed:22245565 KEGG COMPOUND:313-67-7 KEGG COMPOUND:C08469 knapsack:C00001526 CiteXplore:22071594 An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all <em>Aristolochia</em> (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic. pubmed:22373701 8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid pubmed:22126455 8-methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid aristolochin CiteXplore:22245565 chebi_ontology BBFQZRXNYIEMAW-UHFFFAOYSA-N CiteXplore:22373701 AAA Aristolochic acid cas:313-67-7 InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20) CiteXplore:22118289 kegg.compound:C08469 carboxylic acid acid