has_role azathioprine 0 277.03819 277.269 pubmed:25314066 C9H7N7O2S drugcentral:269 pubmed:25581826 LMEKQMALGUDUQG-UHFFFAOYSA-N InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13) pubmed:9273463 pubmed:15476481 pubmed:15628319 pubmed:15973722 pubmed:18336531 pubmed:25443086 pubmed:16397313 cas:446-86-6 MESH:D001379 pubmed:25248004 SNOMEDCT:111165009 pubmed:17381669 pubmed:15199672 A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. pubmed:17970886 pubmed:16344342 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine pubmed:28166217 CHEBI:2948 KEGG DRUG:D00238 drugbank:DB00993 ChEMBL:531141 pubmed:11064448 NCIt:C290 SNOMEDCT:372574004 KEGG DRUG:446-86-6 Imuran (TN) Cn1cnc([N+](=O)[O-])c1Sc1ncnc2ncnc12 pubmed:8738760 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine pubmed:20080917 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine pubmed:9345422 ChemIDplus:446-86-6 pubmed:16764353 pubmed:16954801 wikipedia.en:Azathioprine pubmed:19243907 pubmed:25440430 reaxys:1225351 chebi_ontology kegg.drug:D00238 pubmed:18008354 pubmed:25641386 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine kegg.compound:C06837 antimetabolite antineoplastic agent thiopurine