has_role fulvestrant 0 606.31661 606.782 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol SNOMEDCT:385519002 [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3C[C@@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)[C@@]21[H] A 3-hydroxy steroid that is 17β-estradiol in which the 7α hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. pubmed:21699443 lincs.smallmolecule:LSM-6504 C32H47F5O3S SNOMEDCT:404845006 drugcentral:1255 NCIt:C1379 chebi_ontology CHEBI:31638 pubmed:19369092 ICI-182780 cas:129453-61-8 pubmed:21319872 wikipedia.en:Fulvestrant ICI 182780 kegg.drug:D01161 drugbank:DB00947 fulvestrant InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1 MESH:C070081 VWUXBMIQPBEWFH-WCCTWKNTSA-N fulvestrantum 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol CHEBI:87729 (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol Faslodex pubmed:18683044 steroid antineoplastic agent estrogen receptor antagonist