sapropterin dihydrochloride 0 313.07084 314.173 The dihydrochloride salt of sapropterin. It is used for the diagnosis and treatment of variant forms of phenylketonuria (hyperphenylalaninaemia) associated with tetrahydrobiopterin deficiency. Natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, and nitric oxide synthetase. (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride sapropterin hydrochloride pubmed:20206791 CiteXplore:21645517 kegg.drug:D01798 ChemIDplus:69056-38-8 pubmed:21967857 NCIt:C78088 InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1 pubmed:20667834 reaxys:12490572 pubmed:21077779 CiteXplore:21967857 pubmed:20714359 CiteXplore:20714359 CiteXplore:22112818 Reaxys:12490572 (6R)-tetrahydrobiopterin dihydrochloride CiteXplore:20418136 KEGG DRUG:D01798 pubmed:21645517 Cl.Cl.[H][C@]1([C@@H](O)[C@H](C)O)CNc2nc(N)nc(=O)c2N1 CiteXplore:20667834 CiteXplore:20830319 CiteXplore:22310224 pubmed:20556789 Beilstein:4613446 RKSUYBCOVNCALL-NTVURLEBSA-N C9H15N5O3.2HCl (6R)-tetrahydrobiopterin hydrochloride chebi_ontology SNOMEDCT:434239009 pubmed:20179079 CiteXplore:20556789 sapropterin dihydrochloride pubmed:21646032 CiteXplore:20179079 CiteXplore:21646032 pubmed:20418136 sapropterin 2HCl CiteXplore:21077779 beilstein:4613446 cas:69056-38-8 pubmed:22112818 pubmed:22310224 CiteXplore:20206791 pubmed:20830319 ChEMBL:775726 CHEBI:32120 (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride KEGG DRUG:69056-38-8 ionic salt