chemical entity
tolvaptan
0
448.15537
448.95
pubmed:34070416
pubmed:38509003
pubmed:37516894
pubmed:33078835
wikipedia.en:Tolvaptan
pubmed:37845430
pubmed:38652561
pubmed:12742979
pubmed:34476570
pubmed:37466863
pubmed:34386666
OPC 41061
kegg.drug:D01213
chebi_ontology
pubmed:38494546
CHEBI:32246
drugbank:DB06212
pubmed:37214762
pubmed:37587049
pubmed:38710808
cas:150683-30-0
pubmed:38512373
pubmed:38337413
pubmed:34554640
pubmed:37845144
rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
(+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide
drugcentral:4110
Samsca
Jynarque
(+-)-tolvaptan
pubmed:38562967
tolvaptan
pubmed:38097698
pubmed:37982946
pubmed:38396765
pubmed:38606040
pubmed:16211205
pubmed:38608748
(RS)-tolvaptan
rac-N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
pubmed:38717378
OPC-41061
pubmed:38344178
C26H25ClN2O3
Jinarc
pubmed:38288467
RS-tolvaptan
pubmed:38423003
pubmed:37916285
pubmed:34526469
pubmed:38616432
A racemate comprising of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-tolvaptan. It is a selective vasopressin V<small><sub>2</sub></small> receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency.
pubmed:38577748
tolvaptanum
pubmed:38468548
pubmed:38414126
pubmed:34514204