carboxylic acid 4-phenylbutyric acid 0 164.08373 164.204 CiteXplore:20399799 pubmed:19918981 MESH:C075773 ChemIDplus:1821-12-1 CiteXplore:22359472 4-phenylbutanoic acid CiteXplore:21894430 pdb-ccd:CLT CiteXplore:19918981 InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12) pubmed:21726539 metacyc.compound:CPD-14367 pubmed:20399799 pubmed:21237159 pubmed:21887297 CHEBI:41500 drugcentral:24 CiteXplore:22101259 omega-Phenylbutanoic acid pubmed:22359472 gamma-Phenyl-n-butyric acid NIST Chemistry WebBook:1821-12-1 Benzenebutyric acid O=C(O)CCCc1ccccc1 4-phenylbutanoic acid pubmed:22101259 CiteXplore:21237159 reaxys:638180 gamma-phenylbutyric acid CHEBI:64058 Reaxys:638180 lincs.smallmolecule:LSM-5751 ChEMBL:497873 CiteXplore:21726539 pubmed:21894430 NCIt:C63699 PBA C10H12O2 hmdb:HMDB0000543 cas:1821-12-1 chebi_ontology OBKXEAXTFZPCHS-UHFFFAOYSA-N 4-PHENYL-BUTANOIC ACID A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the γ-globin gene and affects hPPARγ activation. CiteXplore:21887297 4-Phenyl-n-butyric acid omega-phenylbutyric acid acid