has_role isoprenoid antineoplastic agent carboxamide 4-hydroxyphenyl retinamide 0 391.25113 391.555 CiteXplore:20878269 CHEBI:42588 CiteXplore:21674264 KEGG DRUG:D04162 15-[(4-hydroxyphenyl)amino]retinal N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE CiteXplore:22183330 pubmed:22183330 CiteXplore:22094120 pubmed:22162577 pubmed:22094120 CiteXplore:22280430 kegg.drug:D04162 pubmed:22382323 CiteXplore:20978709 pubmed:22387538 CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1 pubmed:22323082 CiteXplore:22162577 cas:65646-68-6 all-trans-4'-Hydroxyretinanilide fenretinidum 4-hydroxy(phenyl)retinamide AKJHMTWEGVYYSE-FXILSDISSA-N 15-[(4-hydroxyphenyl)amino]retinal pubmed:21964808 pubmed:22350416 CiteXplore:21241664 CiteXplore:21319187 pubmed:20978709 drugbank:DB05076 C26H33NO2 CiteXplore:22387538 CiteXplore:22221098 CiteXplore:21964808 ChemIDplus:65646-68-6 CiteXplore:22382323 N-(4-Hydroxyphenyl)retinamide CiteXplore:22323082 MESH:D017313 N-(4-hydroxyphenyl)all-trans retinamide 4-HPR pubmed:22221098 pdb-ccd:FEN reaxys:5769490 pubmed:21674264 A retinoid obtained by formal condensation of the carboxy group of <i>all</i>-<i>trans</i> retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids. pubmed:21319187 pubmed:20878269 pubmed:22280430 fenretinida ChEMBL:100853 NCIt:C1098 fenretinide chebi_ontology Reaxys:5769490 CiteXplore:22350416 pubmed:21241664 InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+ amide